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Metagenics Estrovera Tablets, 90 Count Estrovera by Metagenics is a dietary supplement that has been proven very effective at significantly reducing not only hot flashes but also other symptoms that often accompany menopause. What makes Estrovera by Metagenics work so well is its key ingredient, a special extract of Siberian Rhubarb called ERr 731. Women who take Estrovera by Metagenics as directed can enjoy a number of important health benefits: Reduces the occurrence of hot flashes associated with menopause. Promotes reduction of mood swings and irritability by helping to keep the emotions on an even keel. Helps to reduce such menopausal symptoms as night sweats, insomnia, loss of libido and vaginal dryness.